Curatopes Melanoma

Curatopes Melanoma is a comprehensive database of predicted non-mutated peptide epitopes derived from genes which are overly expressed in a group of 32 melanoma biopsies compared to healthy tissues, and which were filtered against expression in a curated list of survival-critical tissues. The database has applications in facilitating epitope selection and trial design.Curatopes黑色素瘤数据库是一款综合性数据库，收录了相较于健康组织、在32例黑色素瘤活检组织中呈过表达的基因所推导得到的预测性未突变肽表位（peptide epitopes）；该数据集还针对经精选的生存关键组织的表达情况完成了筛选。本数据库可用于辅助表位筛选与临床试验设计。

搜集汇总

背景与挑战

背景概述

Curatopes Melanoma是一个预测性非突变肽表位数据库，这些表位来源于32个黑色素瘤活检中过度表达的基因（相较于健康组织），并经过关键生存组织表达筛选。该数据库主要用于支持表位选择和临床试验设计。