Task-Based Anthropomorphic CT Phantom for Radiomics Stability and Discriminatory Power Analyses (CT-Phantom4Radiomics)

The aims of this dataset are to determine the stability of radiomics features against computed tomography (CT) parameter variations and to study their discriminative power concerning tissue classification using a 3D-printed CT phantom based on real patient data.
A radiopaque 3D phantom was developed using real patient data and a potassium iodide solution paper-printing technique. Normal liver tissue and 3 lesion types (benign cyst, hemangioma, and metastasis) were manually annotated in the phantom [2]. 240 CT series with 8 parameter variations of reconstruction algorithms, reconstruction kernels, slice thickness, and slice spacing are available.
The conclusions of our preliminary study [1] showed that the differences in radiomics feature values obtained from different types of liver tissue are generally greater than the intraclass differences resulting from CT parameter variations.
[1] Jimenez del-Toro, O. et al. (2021) DOI: 10.1097/rli.0000000000000795
[2] Bach, M. et al (2023) DOI: 10.1002/mp.16373