Additional file 6: Table S2. of deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution

突变特征提取

The mutational signature contribution to each TCGA tumor sample studied as determined by deconstructSigs and WTSI Mutational Signature Framework. The full published set of mutational signatures [4] wa

DataCite Commons2024-12-17 更新50

Supplementary data for Islam et al. 2022 - Downsampling of whole genomes

基因组测序

突变特征提取

All results from the de novo extraction of mutational signatures from downsampling of whole-genome sequenced samples to whole-exomes.

NIAID Data Ecosystem40

Supplementary data for Islam et al. 2022 - Benchmark of initialization, normalization and objective function

突变特征提取

NMF算法基准测试

All results from the benchmarking of the different options available in SigProfilerExtractor for matrix normalization, NMF initialization, and NMF objective function.

Figshare2022-08-01 更新10

Supplementary data for Islam et al. 2022 - Downsampling of whole genomes

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