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Cryo-EM structure of a SUR1/Kir6.2 ATP-sensitive potassium channel in the presence of Aekatperone in the closed conformation

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Protein Data Bank Japan2025-04-09 更新2026-04-19 收录
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Cryo-EM structure of a SUR1/Kir6.2 ATP-sensitive potassium channel in the presence of Aekatperone in the closed conformation Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ATP-sensitive inward rectifier potassium channel 11, ... Authors: Driggers, C.M, ElSheikh, A, Shyng, S.-L. Deposit date: 2024-08-30 Release date: 2025-02-12 Last modified: 2025-04-09 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: AI-based discovery and cryoEM structural elucidation of a K ATP channel pharmacochaperone. Elife, 13, 2025
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2024-08-30
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