CuI/I<sub>2</sub>-Promoted Electrophilic Tandem Cyclization of 2-Ethynylbenzaldehydes with <i>ortho</i>-Benzenediamines: Synthesis of Iodoisoquinoline-Fused Benzimidazoles
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An efficient tandem route to the synthesis of iodoisoquinoline-fused benzimidazole derivatives including an iodocyclization strategy has been developed. In the presence of CuI, a variety of 2-ethynylbenzaldehydes underwent the tandem reaction with benzenediamines and iodine to afford the corresponding iodoisoquinoline-fused benzimidazoles in moderate to good yields.
创建时间：
2016-02-24
