Here we report our observations that have led us to propose that the transcription elongation factor NusA promotes a novel class of transcription-coupled repair (TCR) in addition to its previously pro

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Human MLH1 Protein Participates in Genomic Damage Checkpoint Signaling in Response to DNA Interstrand Crosslinks, while MSH2 Functions in DNA Repair

DNA损伤修复机制

错配修复蛋白功能

DNA interstrand crosslinks (ICLs) are among the most toxic types of damage to a cell. For this reason, many ICL-inducing agents are effective therapeutic agents. For example, cisplatin and nitrogen mu

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Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

酶-RNA复合物结构

DNA损伤修复机制

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

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Crystal structure of the Tudor domain of human ERCC6-L2

蛋白质晶体结构解析

DNA损伤修复机制

Crystal structure of the Tudor domain of human ERCC6-L2 Descriptor: DNA excision repair protein ERCC-6-like 2 Authors: Newman, J.A, Gavard, A.E, Nathan, W.J, Pinkas, D.M, von Delft, F, Arrowsmith, C.H

Protein Data Bank Japan2024-01-24 更新50