Spearman rank correlations (RT qPCR data <i>vs.</i> metabolite data)^a, in the expanded patient cohort, of purine/thiopurine related genes.^b

aGenes that showed a significant correlation (P<0.05) between relative gene expression levels (RT qPCR data) and the concentration of 6-TGN, meTIMP or the meTIMP/6-TGN concentration ratio in the expanded patient cohort (n = 54). bNone of the genes selected by means of their potential relationship with the mechanism, metabolism or transport of purines/thiopurines fulfilled the established significance level (P<0.001) in the microarray data.