Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition
收藏Protein Data Bank Japan2024-05-22 更新2026-04-11 收录
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Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition Descriptor: 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3') Authors: Malard, F, Campagne, S. Deposit date: 2023-11-20 Release date: 2024-03-06 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design. Nucleic Acids Res., 52, 2024
创建时间：
2023-11-20
