Total Synthesis of Chaetoquadrins A–C
收藏Figshare2016-02-20 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Total_Synthesis_of_Chaetoquadrins_A_C/2447980
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The first total synthesis of the monoamine oxidase inhibitors chaetoquadrins A–C has been accomplished. Key steps in the synthesis include an aromatic Claisen rearrangement, asymmetric boron aldol reaction and acid-mediated spiroketalization. Comparison of spectral data for the synthetic spiroketals confirmed the proposed structure for these natural products.
创建时间:
2016-02-20



