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Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjogren's syndrome via suppression of the CX3CL1/CX3CR1 axis

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1169323
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Non-obese diabetic (NOD)/Ltj mice (pSS model) were intravenously administered with adeno-associated viruses of GFP and MYDGF at 11 weeks of age. Mice were sacrificed 5 weeks after MYDGF treatment, and submandibular glands were collected. mRNA sequencing and bioinformatics predicted the mechanism of the therapeutic effect of MYDGF.
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2024-10-05
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