Crystal Structure of compound 10 covalently bound to K-Ras G12C
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Crystal Structure of compound 10 covalently bound to K-Ras G12C Descriptor: (3R)-N-(6-bromonaphthalen-2-yl)-3-hydroxy-1-propanoyl-L-prolinamide, GLYCEROL, GTPase KRas, ... Authors: Nnadi, C.I, Jenkins, M.L, Gentile, D.R, Bateman, L.A, Zaidman, D, Balius, T.E, Nomura, D.K, Burke, J.E, Shokat, K.M, London, N. Deposit date: 2017-08-22 Release date: 2018-01-31 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Novel K-Ras G12C Switch-II Covalent Binders Destabilize Ras and Accelerate Nucleotide Exchange. J Chem Inf Model, 58, 2018
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2017-08-22
