Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice

ChEBI2015-03-11 更新2026-07-21 收录

神经退行性机制

铁代谢紊乱研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-66730 数据链接链接失效反馈

官方服务：

资源简介：

Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice

创建时间：

2015-03-11

Examination of gene expression in cerebellum and hippocampus for mouse C57BL/6J WT and nmf205-/-

神经退行性机制

细胞应激通路

Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw

NIAID Data Ecosystem100

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons

神经退行性机制

功能障碍研究

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

Additional file 3 of Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy

单细胞转录组学

神经退行性机制

Additional file 3: Table S3. RNA integrity number for PBMC samples.

Figshare2024-09-11 更新40

Misconnecting the dots: altered mitochondrial protein-protein interactions and their role in neurodegenerative disorders

蛋白质相互作用

神经退行性机制

Introduction: Mitochondria (mt) are protein-protein interaction (PPI) hubs in the cell where mt-localized and associated proteins interact in a fashion critical for cell fitness. Altered mtPPIs are li

NIAID Data Ecosystem70

Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS

神经退行性机制

细胞特异性翻译组

Ubiquitous expression of ALS-causing mutations in superoxide dismutase 1 (SOD1) provoke non-cell autonomous paralytic disease. By combining ribosome affinity purification and high-throughput sequencin

NIAID Data Ecosystem40

Disrupted iron homeostasis causes dopaminergic neurodegeneration in mice

资源简介：

相关数据集