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Deletion of NuRD component Mta2 in nephron progenitor cells causes developmentally programmed FSGS

NIAID Data Ecosystem2026-05-01 收录

发育遗传学

肾小球疾病机制

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE246695 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-11-05

发育遗传学

基因功能验证

Additional file 12: Source Data File 1. Zip file with the raw unedited blot images. Sections of these 3 images were used to create Supplemental Fig. 2.

DataCite Commons2023-05-05 更新120

E-GEOD-1482

发育遗传学

转录组分析

Transcription profiling of mouse NF+/- and control samples to determine the molecular basis of the neurodevelopmental changes that result from the primary gene mutation

NIAID Data Ecosystem50

Summary of the Developmental Phenotypes of Stu Mutants.

发育遗传学

模式生物表型

*The percentage of each phenotype. **Total number of examined animals. ***For the sterile adult, vulva morphology was examined (see Materials and Methods). Pvl: protruding vulva; Vul: vulvaless.

NIAID Data Ecosystem20

Expression data from wild-type and Robo2 homozygous kidneys

基因表达谱分析

发育遗传学

We used microarrays to detail the global gene expression in tissues from wild-type and Robo2 homozygous kidneys. Tissues from E17 wild-type and Robo2 homozygous kidneys were for RNA extraction and hy

NIAID Data Ecosystem90

5'-monophosphate-dependent small RNA sequencing from ego-1(om84) and control adult C. elegans hermaphrodites

RNA调控机制

发育遗传学

Cellular RdRPs play a critical role in the development of many organisms. Using high-throughput small RNA and messenger RNA sequencing we found that the Caenorhabditis elegans RdRP, EGO-1, is require

NIAID Data Ecosystem20

Deletion of NuRD component Mta2 in nephron progenitor cells causes developmentally programmed FSGS

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