Synthesis of 9‑Substituted Triptycene Building Blocks for Solid-Phase Diversification and Nucleic Acid Junction Targeting
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下载链接：
https://figshare.com/articles/dataset/Synthesis_of_9_Substituted_Triptycene_Building_Blocks_for_Solid_Phase_Diversification_and_Nucleic_Acid_Junction_Targeting/2300683
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资源简介：
Triptycenes have
been shown to bind nucleic acid three-way junctions,
but rapid and efficient methods to diversify the triptycene core are
lacking. An efficient synthesis of a 9-substituted triptycene scaffold
is reported that can be used as a building block for solid-phase peptide
synthesis and rapid diversification. The triptycene building block
was diversified to produce a new class of tripeptide–triptycenes,
and their binding abilities toward d(CAG)·(CTG) repeat junctions
were investigated.
创建时间：
2016-02-17
