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Genome-wide analysis of B lymphocytes derived from human pluripotent stem cells, neonatal and adult sources

ChEBI2014-06-20 更新2026-07-21 收录

淋巴细胞发育

多能干细胞分化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53572 数据链接链接失效反馈

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Genome-wide analysis of B lymphocytes derived from human pluripotent stem cells, neonatal and adult sources

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创建时间：

2014-06-20

多能干细胞分化

I型干扰素

Upon virus infection,pluripotent stem cells neither induce nor respond to canonical Type I interferons (IFN-I). To better understand this biology,we characterized induced pluripotent stem cells (iPSCs

NIAID Data Ecosystem70

IL-7Rα and E47: independent pathways required for development of multipotent lymphoid progenitors

淋巴细胞发育

转录因子信号通路

Mice that lack the transcription factors encoded by the E2A gene or the receptor for interleukin 7 (IL-7R) have severe overlapping defects in lymphocyte development. Here, we show that E2A proteins ar

PubMed Central2002-01-15 更新60

Derivation of trophoblast stem cells from naïve human pluripotent stem cells

滋养层干细胞衍生

多能干细胞分化

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem60

Simple differentiation method using FBS identifies DUSP6 as a marker for fine-tuning of FGF-ERK signaling activity in human pluripotent stem cells

多能干细胞分化

FGF-ERK信号调控

Assessment of differentiation potential is a basic requirement to obtain qualified human pluripotent stem cells (hPSCs). Here, we report a simple differentiation method using fetal bovine serum (FBS)

NIAID Data Ecosystem70

The B cell identity factor Pax5 regulates distinct transcriptional programs in early and late B lymphopoiesis. Mus musculus

淋巴细胞发育

转录组调控

Pax5 controls the identity and development of B cells by repressing lineage-inappropriate genes and activating B-cell-specific genes. Here, we used genome-wide approaches to identify Pax5 target genes

NIAID Data Ecosystem60

Genome-wide analysis of B lymphocytes derived from human pluripotent stem cells, neonatal and adult sources

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