pat-2 mutants contain more apoptotic cells during mid-embryogenesis than the wild-type.
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aThe number of cell corpses in each genotype was scored at the indicated embryonic stage.bEmbryos that showed normal embryogenesis were scored as nonPat and those paralyzed at the 2-fold stage were scored as Pat.cHomozygous progeny of unc-79(e1068) pat-2(st567)/dpy-17(e164) heterozygous mothers.dNon-transgenic progeny of unc-79(e1068) pat-2(st567); Ex[Ppat-2pat-2::gfp] mothers.eNon-transgenic progeny of unc-79(e1068) pat-2(st567); ced-3(n717); Ex[Ppat-2pat-2::gfp] mothers.fHomozygous progeny of pat-3(st564)/qC1 dpy-19(e1259) glp-1(q339) heterozygous mothers. pat-2, ina-1, and pat-3 single mutants were compared to the wild-type (**p#p##ppat-2(st567)d embryos treated with pat-2 RNAi are not distinguishable from those of pat-2(st567)d or pat-2(RNAi) embryos at the same stage. Data are presented as the mean ± standard deviation (SD) for >15 embryos per stage.
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2015-12-02



