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Highly optimized CNS penetrant inhibitors of EGFR Exon20 Insertion Mutations

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Protein Data Bank Japan2025-02-26 更新2026-04-19 收录
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Highly optimized CNS penetrant inhibitors of EGFR Exon20 Insertion Mutations Descriptor: Epidermal growth factor receptor, SULFATE ION, ~{N}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide Authors: Hargreaves, D. Deposit date: 2024-08-06 Release date: 2025-02-12 Last modified: 2025-02-26 Method: X-RAY DIFFRACTION (2.218 Å) Cite: Highly Optimized CNS Penetrant Inhibitors of EGFR Exon20 Insertion Mutations. J.Med.Chem., 68, 2025

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2024-08-06
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