Bulk RNA-sequencing of FUS H517Q and healthy iPSC-derived motor neurons

We sought to investigate changes in gene expression levels including changes in pri-microRNAs in FUS H517Q motor neurons Motor neurons were differentiated from patient-derived FUS H517Q and healthy iPSCs, and harvested at day 30. We performed gene expression profiling analysis using data obtained from bulk RNA-seq. Overall design: Comparative gene expression profiling using RNA-seq analysis of FUS H517Q and healthy motor neurons.