CPEB4-mediated translational regulation of LPS response in BMDMs

Here we show that the RNA-binding protein CPEB4 sustains the expression of anti-inflammatory factors in LPS-stimulated BMDMs, by binding to the corresponding mRNAs and promoting their stabilization. in macrophages. RNA-immunoprecipitation sequencing of CPEB4-associated mRNAs in Wild type and CPEB4-KO BMDMs