Cryo-EM structure of human uMtCK1 in complex with ADP and covalent inhibitor CKi

Cryo-EM structure of human uMtCK1 in complex with ADP and covalent inhibitor CKi Descriptor: (2S)-4-(chloroacetyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Creatine kinase U-type, ... Authors: Demir, M, Koepping, L, Zhao, J, Sergienko, E. Deposit date: 2024-03-13 Release date: 2025-02-12 Last modified: 2025-04-16 Method: ELECTRON MICROSCOPY (2.89 Å) Cite: Structural basis for substrate binding, catalysis, and inhibition of cancer target mitochondrial creatine kinase by a covalent inhibitor. Structure, 33, 2025