An uncharacterized gene, C7orf26 was expected to function with the integrator complex in mRNA splicing. To address the involvement of mRNA splicing, we performed microarray analysis of HeLa/C7orf26 si
Fidelity of 3´-splice site (3´SS) selection by the spliceosome is critical for proper gene expression but is a daunting task considering the low complexity of the 3´SS consensus YAG. Here we show that
The depletion and deletion of RAVER1 substantially impairs the 2D-proliferation of tumor cells, vitality in 3D cell models and the growth of subcutaneous xenografts in nude mice. Disturbance of RAVER1