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The gut metagenome of experimental autoimmune uveitis mice

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https://www.ncbi.nlm.nih.gov/sra/SRP584402
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This study aims to investigate the effect of PD-L1 knockout on gut microbiota in an experimental autoimmune uveitis (EAU) model. EAU was induced via immunization with interphotoreceptor retinoid-binding protein peptide 651-670 (IRBP651-670) in either wild-type or PD-L1 knockout C57BL/6J female mice. Sham adjuvant was administered to WT or PD-L1 KO mice as healthy controls. The characteristics of gut microbiota were analyzed using metagenomic sequencing.
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2025-05-13
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