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Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, Cryptococcus neoformans protein farnesyltransferase alpha subunit, ... Authors: Hast, M.A, Beese, L.S. Deposit date: 2011-06-14 Release date: 2011-08-03 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens. J.Biol.Chem., 286, 2011

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2011-06-14
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