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CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ATP

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Protein Data Bank Japan2025-12-17 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7bkp
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CryoEM structure of disease related M854K MDA5-dsRNA filament in complex with ATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Interferon-induced helicase C domain-containing protein 1, MAGNESIUM ION, ... Authors: Singh, R, Herrero del Valle, A, Yu, Q, Modis, Y. Deposit date: 2021-01-16 Release date: 2021-11-17 Last modified: 2025-12-17 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nat Commun, 12, 2021
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2021-01-16
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