Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33068
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Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR33068 Descriptor: 1,2-ETHANEDIOL, 2-chloro-N-(6-cyanopyridin-3-yl)-5-nitrobenzamide, Nuclear receptor corepressor 1, ... Authors: MacTavish, B.S, Kojetin, D.J. Deposit date: 2022-12-21 Release date: 2024-04-17 Last modified: 2025-04-30 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Ligand efficacy shifts a nuclear receptor conformational ensemble between transcriptionally active and repressive states. Nat Commun, 16, 2025
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2022-12-21
