Shengjiang Xiexin Decoction in the treatment of Clostridium difficile infection Related pharmacodynamic, microbiomics, and metabolomics datasets

We hypothesized that the ameliorative effect of SXD on CDI is related to the modulation of gut microbiota composition and metabolism by SXD. In the present study, we first investigated the effect of SXD on CDI mice. Then, we used 16s rDNA gene sequencing, non-targeted metabolomics, and serum pharmacochemistry to detect intestinal flora, metabolism, and blood prototype drug profiles in mice.