Colistin resistance in clinical Enterobacteriaceae isolates from the Western Cape of South Africa
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Colistin resistant E. coli and Klebsiella spp. isolates were collected from the microbiology laboratory at Tygerberg Hospital during 2016 and 2017. Strains were mostly unrelated in 2016 based on rep-PCR, however the majority of the 2017 E. coli isolates were related based on rep-PCR, MLST and SNP analyses. mcr-1 was responsible for >50% of colistin resistance, but mutations in pmrB and disruption of mgrB were common in E. coli and Klebsiella spp. respectively.
创建时间：
2020-10-19
