Xenobiotic-responsive Nuclear Receptors in Transcriptional Effects Upon Perfluoroalkyl Acid Exposure in Diverse Species
收藏Alliance of Genome Resources2026-08-01 收录
官方服务:
资源简介:
Keywords: gene expression/microarray
应用场景:
相关数据集
The IR-1 at −291/−279 is required for 9cRA-, but not for CDCA-mediated induction of the human SHP promoter.
DLD-1 cells were transfected with hFXR and hRXRα expression plasmids and various hSHP promoter constructs as indicated. Cells were treated with or without 100 µmol/L CDCA and/or 1 µmol/L 9cRA. The syn
NIAID Data Ecosystem40
Transcriptional Silencing Is Defined by Isoform- and Heterodimer-Specific Interactions between Nuclear Hormone Receptors and Corepressors
Nuclear hormone receptors are ligand-regulated transcription factors that play critical roles in metazoan homeostasis, development, and reproduction. Many nuclear hormone receptors exhibit bimodal tra
PubMed Central20
Phenobarbital Induces Cell Cycle Transcriptional Responses in Mouse Liver Humanized for Constitutive Androstane and Pregnane X Receptors (mRNA). Mus musculus
The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are closely related nuclear receptors involved in drug metabolism and play important roles in the mechanism of phenobarbita
NIAID Data Ecosystem20
Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element
Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element Descriptor: CHLORIDE ION, GLYCEROL, RARb2 DR5 Response Element, ... Authors: McEwen,
Protein Data Bank Japan2024-01-24 更新30
Transcriptional effects of LXR nuclear receptors on M-CSF-derived macrophages
Analysis of the role of LXR transcriptions factors on the transcriptional signature of human M-CSF-dependent monocyte-derived macrophages. Methods: Human Peripheral Blood Mononuclear Cells (PBMC) were
NIAID Data Ecosystem20



