BWH MS Genetic Collection

The main objective of this GWA study is to identify Multiple Sclerosis (MS) susceptibility loci. Whole-genome association analysis was performed on 924 individuals genotyped on the Affymetrix 6.0 Genechip. The cohort consisted of 860 clinically diagnosed MS patients and 64 control subjects.]]> Diagnosis of multiple sclerosis (McDonald criteria), age > 18. Primary progressive subjects excluded.]]> Subjects were all collected through the Partners MS center in Boston, Massachusetts (http://www.partnersmscenter.org/). Data were generated as part of a collaboration with Affymetrix, Inc. Genotypes were produced at the Broad Institute's Center for genotyping.]]>