Supplementary Table S10 from A Functional Survey of the Regulatory Landscape of Estrogen Receptor–Positive Breast Cancer Evolution

Supplementary Table S10: Metadata of the clinical cohort profiled by SIDV. S10.1: for each donor, from which genetic material from matched normal, primary, and metastatic samples were derived, the following information is provided: the identifier for the samples; the center where the samples were collected; the sequencing batch; the age of diagnosis; the clinical features of the primary tumors; the indication of the metastatic sites. Legend: ER = estrogen-receptor alpha; PR = progesterone receptor; pct = percentage; HR = hormone therapy. S10.2: for each triplet of matched normal, primary and metastasis derived material, and separately for each one of the 100 donors, sequencing statistics are provided. Sequencing depth, fraction of the reads mapping to oligo baits, mean coverage on baits and corresponding fold-enrichment, and on-target mean coverage, are shown. The percentages (pct) of targeted bases covered at least 10x, 30x, 50x or 100x are also indicates.