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Asymmetric Synthesis of Indole Homo-Michael Adducts via Dynamic Kinetic Friedel–Crafts Alkylation with Cyclopropanes

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NIAID Data Ecosystem2026-03-07 收录
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An enantioconvergent Friedel–Crafts alkylation of indoles with donor–acceptor cyclopropanes is described. The reaction is catalyzed by pybox•MgI2 and proceeds via a type I dynamic kinetic asymmetric transformation (DyKAT).

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2016-02-19
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