sFLT1 gene expression as a mediator in the association between arsenic exposure and birth weight.

N = number of subjects; CI = Confidence Interval; SGA = Small for Gestational Age; g = gram;* = p-value Interpretation of the estimate (β): Model 1) Difference in birth weight between high arsenic exposed and low to median exposed newborns; Model 2) Log2(fold change) in sFLT1 expression between high arsenic exposed and low to median exposed newborns; Model 3) Difference in birth weight for a duplication in sFLT1 expression; Model 4) For sFLT1: Difference in birth weight for a duplication in sFLT1 expression - For arsenic: Difference in birth weight between high arsenic exposed and low to median exposed newborns.The associations in model 1 were adjusted for gender, gestational age, smoking during pregnancy, and parity; The associations in model 2 were adjusted for gender and gestational age; The associations in model 3 and 4 were adjusted for gender, gestational age, smoking during pregnancy, parity, and the interaction between gender and sFLT1.