Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 70 (1084352)
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Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 70 (1084352) Descriptor: 1-[8-(4-bromanyl-3-fluoranyl-phenyl)sulfonyl-5-oxa-2,8-diazaspiro[3.5]nonan-2-yl]-2-chloranyl-ethanone, 14-3-3 protein sigma, C-RAF peptide pS259, ... Authors: Konstantinidou, M, Vickery, H, Pennings, M.A.M, Virta, J, Visser, E.J, Oetelaar, M.C.M, Overmans, M, Neitz, J, Ottmann, C, Brunsveld, L, Arkin, M.R. Deposit date: 2023-10-10 Release date: 2025-04-23 Last modified: 2026-03-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Modulation of the 14-3-3 sigma /C-RAF "Auto"inhibited Complex by Molecular Glues. J.Am.Chem.Soc., 148, 2026
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2023-10-10
