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Systems analysis identifies an essential role for SHARPIN in macrophage TLR2 responses (Agilent)

ChEBI2011-08-30 更新2026-07-21 收录

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巨噬细胞分子机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-29888 数据链接链接失效反馈

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Systems analysis identifies an essential role for SHARPIN in macrophage TLR2 responses (Agilent)

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创建时间：

2011-08-30

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神经抗病毒免疫

Human herpes simplex virus-1 (HSV-1) encephalitis can be caused by inborn errors of the TLR3 pathway resulting in impairment of central nervous system (CNS) cell-intrinsic antiviral immunity. Deficien

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RNAi Induces Innate Immunity through Multiple Cellular Signaling Pathways

RNAi免疫刺激机制

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Background & Aims Our previous results showed that the knockdown of woodchuck hepatitis virus (WHV) by RNA interference (RNAi) led to upregulation of interferon stimulated genes (ISGs) in primary hepa

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Coxsackievirus Cloverleaf RNA Containing a 5′ Triphosphate Triggers an Antiviral Response via RIG-I Activation

RIG-I激动剂抗病毒

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Upon viral infections, pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs) and stimulate an antiviral state associated with the production of type I interfero

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Genome-wide analysis of LPS or PBS challenged DUSP3-KO and WT female mice peritoneal macrophages gene expression

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基因敲除模型

Analysis of gene expression profile in peritoneal macrophage extracted from LPS or PBS challenged DUSP3-/- and WT mice. DUSP3 deletion protects mice from sepsis and endotoxemia. We performed a microa

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CryoEM structure of the TIR domain from AbTir in complex with 3AD

蛋白质结构解析

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CryoEM structure of the TIR domain from AbTir in complex with 3AD Descriptor: Molecular chaperone Tir, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-p

Protein Data Bank Japan2024-06-12 更新30

Systems analysis identifies an essential role for SHARPIN in macrophage TLR2 responses (Agilent)

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