BindingDB Entry 50049142: Identification of a selective inhibitor of transforming growth factorß-activated kinase 1 by biosensor-based screening of focused libraries.

Small molecule binding data for protein Aurora kinase A, Cyclin-dependent kinase 1/G1/S-specific cyclin-D1, Cyclin-dependent kinase 2, Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase, Ephrin receptor, Epidermal growth factor receptor, Epithelial discoidin domain-containing receptor 1, Fibroblast growth factor receptor 2, Focal adhesion kinase 1, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, Leukocyte tyrosine kinase receptor, Macrophage-stimulating protein receptor, Mast/stem cell growth factor receptor Kit, Mitogen-activated protein kinase 14, PKC alpha and beta-2, Protein kinase C iota type/zeta type, Proto-oncogene tyrosine-protein kinase Src, RAC-alpha serine/threonine-protein kinase AKT1, RAF proto-oncogene serine/threonine-protein kinase, SRC, TAK1/TAB1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BRK, Tyrosine-protein kinase Lck, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase receptor FLT3, Tyrosine-protein kinase receptor UFO, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O14965, O43318, P00519, P00533, P05771, P06213, P06239, P06241, P06493, P07947, P07948, P08069, P08581, P10721, P12931, P17252, P21802, P24941, P29317, P29376, P30530, P31749, P35968, P36888, Q02750, Q04912, Q05397, Q05513, Q08345, and Q13882