Genome-wide maps of histone variant H3.3 occupancy in zebrafish cardiomyocytes [H33]
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介：
We report high-throughput profiling of transgenic histone H3.3 in zebrafish cardiomyocytes. The replacement histone H3.3 is deposited at sites of nucleosome turnover including regions of active chromatin. We profile H3.3 in uninjured cardiomyocytes, those undergoing regeneration 14 days after genetic ablation and those proliferating 7 days after Nrg1 stimulated hyperplasia. This study provides a framework for understanding chromatin transitions during adult models of regeneration.
提供机构：
Massachusetts General Hospital
创建时间：
2022-02-20
