Least square means for HbA1c at the different measurements by group and sex.

Legend: solid line = Intervention group, dashed line = usual care group Note. Least square means are based on parameter estimates of sex-stratified hierarchical linear models for HbA1c. Models were adjusted for sex, age, marital status and education, were specified to take into account intra-individual correlation over time and clustering by GP practice (random effect), and included time and time×group-interaction effects.