Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and BVT.13

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and BVT.13 Descriptor: 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, 2-chloro-5-nitro-N-phenylbenzamide, Peroxisome proliferator-activated receptor gamma Authors: Shang, J, Kojetin, D.J. Deposit date: 2024-05-08 Release date: 2024-08-07 Last modified: 2025-04-23 Method: X-RAY DIFFRACTION (2.54 Å) Cite: Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPAR gamma. Elife, 13, 2024