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Sex and tissue differences in estrogen receptor mRNA using ddPCR

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NIAID Data Ecosystem2026-03-10 收录
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https://doi.org/10.7910/DVN/N58KGA
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资源简介:
Estrogen is formed by the enzyme aromatase (CYP19A1) and signals via three identified receptors ERα (ESR1), ERß (ESR2), and the G Protein-Coupled Estrogen Receptor (GPER). Understanding, the relative contribution of each receptor to estrogenic signaling may elucidate the disparate effects of this sex hormone across tissues. Moreover, droplet digital PCR is a novel technology that allows absolute quantification and direct comparison of multiple targets. We hypothesized that utilization of this new technology would reveal tissue- and sex-specific differences in estrogen receptor mRNA.
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2019-01-06
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