Additional file 1 of The expressed mutational landscape of microsatellite stable colorectal cancers

Additional file 1: Table S1. Clinicopathological characteristics and expressed tumor mutational burden in primary colon cancers from TCGA. Table S2. Summarization of the different mutation categories detected by whole-exome sequencing of 126 samples from 121 microsatellite stable CRCs (in-house series). Table S3. Filtering of mutations for allele-specific expression analysis based on RNA sequencing coverage. Table S4. Mutation expression frequency. Table S5. Non-synonymous mutations with high relative allelic expression level (ΔMAF RNAadjusted|DNA > 0.25). Table S6. Overview of CRC cell lines (n = 29). Table S7. Overview of PDOs from resected microsatellite stable CRC liver metastases analyzed by RNA sequencing and drug sensitivity testing.