AGO-bound virus-derived RNA in Influenza infected WT and AGO4 knockout bone marrow derived macrophages performed by Immunoprecipitation following by High Throughput Sequencing

We identified virus-derived RNA bound to AGO in Influenza A or Influenza delNS1-infected macrophages taken from wild-type or Ago4 KO littermate control mice Overall design: Immunoprecipitation of AGO-bound RNA after UV crosslinking using pan AGO antibody in WT or Ago4 KO primary bone marrow-derived macrophages infected with Influenza A (PR/8/1934) or A/PR/8/1934 ?NS1 (MOI 1 for 24h)