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RNA aptamers specific for IL4-treated MSC2 cell line

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NIAID Data Ecosystem2026-03-11 收录
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We performed an unsupervised, high-throughput (HT) sequencing-cell SELEX (systematic evolution of ligands by exponential enrichment) using the MDSC-derived cell line MSC2. Specifically untreated MSC2 and IL4 treated MSC2 were used as negative and positive selector respectively. Selection was started from a 5 ug of 40bp variable region linked to two constant region. HT-SELEX across 11 cycles for the selection of RNA aptamers

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2020-06-23
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