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Multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in picolitre-sized droplets [dataset 3]. Multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in picolitre-sized droplets [dataset 3]

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NIAID Data Ecosystem2026-03-13 收录
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K562 cells were perturbed with drug combinations for 12h in droplets. Subsequently cells were processed to generate liraries for RNA-Seq. Overall design: Control experiments for the multiplex combinatorial drug screen in droplets. Experiments were performed in bulk, droplets or with ERCC spike ins to assess the performance of droplets-based drug screens using gene expression as a readout.

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2022-06-21
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