Mass spectrometry-based proteomics analysis of rat living myocardial slices subjected to cryoinjury.
收藏Figshare2023-09-05 更新2026-04-08 收录
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https://figshare.com/articles/dataset/Mass_spectrometry-based_proteomics_analysis_of_rat_living_myocardial_slices_subjected_to_cryoinjury_/24085131/1
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资源简介：
In this study, we employed living myocardial slices (LMS) as an <i>ex vivo</i> model of cardiac injury to investigate underlying mechanisms and potential therapeutic targets. Cryoinjury was induced in adult rat LMS, resulting in 30% tissue damage. LMS were cultured for 24 hours in biomimetic cultivation chambers while mechanically stretched and electrically stimulated. At the end of the experiment, LMS were split into 2 parts: peri-injury including the injured area plus 1 mm margins, and remote including the rest of the tisse. This proteomics analysis includes three groups: control (uninjured) LMS, injured-peri-injury), and injured-remote. n=3.
提供机构：
Abbas, Naisam; Just, Annette; Korte, Wilhelm; Werlein, Christopher; Fiedler, Jan; Pfanne, Angelika; Fuchs, Maximilian; Ius, Fabio; Weber, Natalie; Pich, Andreas; Perbellini, Filippo; Thum, Thomas; J. G. Waleczek, Florian; Ruhparwar, Arjang
创建时间：
2023-09-05
