Crystal structure of a topoisomerase ATP inhibitor
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Crystal structure of a topoisomerase ATP inhibitor Descriptor: 5-{2-(ethylcarbamoyl)-4-[3-(trifluoromethyl)-1H-pyrazol-1-yl]-1H-pyrrolo[2,3-b]pyridin-5-yl}pyridine-3-carboxylic acid, DNA topoisomerase IV, B subunit Authors: Boriack-Sjodin, P.A, Manchester, J, Hull, K. Deposit date: 2012-04-12 Release date: 2012-08-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV. Bioorg.Med.Chem.Lett., 22, 2012
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2012-04-12
