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Epitope mapping of gp41-specific mAbs.

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https://figshare.com/articles/dataset/_Epitope_mapping_of_gp41_specific_mAbs_/538643
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Cross competition with biotinylated mAbs of known specificity: +, 90–100% inhibition, +/−, 50–90% inhibition, −, <50% inhibition. Binding to different gp41 constructs by ELISA. Minimal linear epitopes using the Pepscan analysis and specificity assignment. C-C, C-C loop; 5HB, 5-helix bundle; FP, fusion peptideShown is also the number of isolates neutralized in the HOS-based and TZM-bl based assays.
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2010-01-20
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