Significant mQTL from GWAS of metabolite factors 1, 2 and 3.

MAF: Minor allele frequency; Add: additive; Dom: dominant.aB: black, W: whitebsex, age and race-specific PC adjusted (4 PCs for whites, 2 PCs for blacks).cmeta-analysis combining discovery and validation cohorts, for race-stratified analyses, adjusted for sex, age and race-specific PCs.Presented are SNPs meeting genomewide significance for association with factor 1 (MCA metabolites), factor 2 (LCDA metabolites) and factor 3 (SCDA metabolites) in race-stratified analyses in the discovery cohort (p≤10−6) also showing nominal association (p≤0.05) in the validation cohort, ranked by meta-analysis p-value.