Predicted pathways regulated by miRNAs expressed in the plasma microvesicles and PBMC fractions.

Predicted targets were compiled separately using Sanger miRBase and TargetScan for the top nine miRNAs expressed in the plasma microvesicles and PBMC (Table 1). The common predicted targets were subsequently analyzed by IPA software to determine predicted pathways regulated by the miRNAs. Fisher's exact test was used to calculate a p-value determining the probability of the association between the genes in the dataset and the canonical pathway.