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Crystal structure of human ZIP kinase in complex with a tetracyclic pyridone inhibitor (Pyridone 6)

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Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Crystal structure of human ZIP kinase in complex with a tetracyclic pyridone inhibitor (Pyridone 6) Descriptor: 1,2-ETHANEDIOL, 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, CHLORIDE ION, ... Authors: Turnbull, A.P, Berridge, G, Fedorov, O, Pike, A.C.W, Savitsky, P, Eswaran, J, Papagrigoriou, E, Ugochukwa, E, von Delft, F, Gileadi, O, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. Deposit date: 2006-10-31 Release date: 2006-11-07 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites. Embo J., 27, 2008
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2006-10-31
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