amino acid cluster analysis (A2CA)

A2CA is a Shiny app-based R script to visualize a multiple sequence alignment (MSA) in a phylogenetic context. Therefore, the input of a MSA and a corresponding phylogenetic tree is required. Further, characteristics of selected amino acids can be computed and included in the visualization. The data can be used for correlation with an external data set like melting points or enzyme activity.A2CA uses your standard web browser as backend. The software was developed using Firefox but should run stable on every Chromium based browser (Chrome, Edge, Firefox etc.).The software is shipped in an .zip folder. The folder has to be unpacked and A2CA can be run without further installation. Program execution can be initiated by double clicking the “run.vbs” file. As the visual basic script (vbs) is a file format developed by the Microsoft Corporation, it will only work on Windows operating systems.